Cisplatin cancer research
WebCisplatin or (SP-4-2)-diamminedichloridoplatinum(II) is one of the most potential and widely used drugs for the treatment of various solid cancers such as testicular, ovarian, head … WebAnnexin XI immunoreactivity inversely correlated with in vitro cisplatin resistance in ovarian cancers (P = 0.01). Decreased expression of Annexin XI is characteristic for cisplatin …
Cisplatin cancer research
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WebJul 14, 2014 · For example, DMSO was used in 34% of Cancer Research and 20% of Molecular Cancer Therapeutics articles that were examined. In the clinic, cisplatin is … Web2 days ago · Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options. Researchers...
WebTreatment of lung cancer, the most common type of carcinoma, is difficult due to disease progression at the time of diagnosis, causing a high mortality rate. 1, 32 Cisplatin … WebSep 15, 2024 · Cisplatin is the prototype platinum coordination complex classified as an alkylating agent and used intravenously in the treatment of several forms of cancer. Cisplatin has been associated with a low rate of serum enzyme elevations and with rare cases of clinically apparent, acute liver injury.
Web2 days ago · Researchers at the University Hospital Bonn (UKB) have now been able to elucidate a mechanism underlying cisplatin resistance in testicular cancer. Using … WebJul 7, 2014 · DMSO was the most heavily utilized in-lab solvent. For example, DMSO was used in 34% of Cancer Research and 20% of Molecular Cancer Therapeutics articles that were examined. In the clinic, cisplatin is typically provided as a lyophilized powder in a vial containing 50 mg cisplatin, 450 mg NaCl and 500 mg mannitol.
WebOct 28, 2024 · There have been reports confirming the role of apoptosis as an essential mode of action for several anti-tumour agents, such as alkylating agents including the widely used cisplatin and 1,3- bis (2-chloroethyl)-1-nitrosourea (BCNU) [ 22 ], ionising radiation [ 23 ], topoisomerase inhibitor etoposide, taxol [ 24 ], the tumour necrosis factor (TNF) …
Web2 days ago · Researchers at the University Hospital Bonn (UKB) have now been able to elucidate a mechanism underlying cisplatin resistance in testicular cancer. Using … how was the bust of nefertiti madeWebJan 14, 2024 · Cisplatin is one of many chemotherapy drugs. What you will not hear at a cancer center or from your oncologist is how effective is Cisplatin. Introduction When … how was the byzantine empire startedWebAnnexin XI immunoreactivity inversely correlated with in vitro cisplatin resistance in ovarian cancers (P = 0.01). Decreased expression of Annexin XI is characteristic for cisplatin-resistant cancer cells and may contribute to tumor recurrence. Annexin XI may be a potential marker for chemoresistance and earlier recurrence of ovarian cancer ... how was the calculator inventedWebAug 1, 2024 · Fueling new research and discovery The discovery, patenting and FDA approval of cisplatin—often called the “penicillin of cancer drugs”—was a 13-year process, an unusually brief period of time in the research world. how was the byzantine empire establishedWebPatients with a tumor response or stabilization continued to receive cisplatin (80 mg/m) and oral vinorelbine (40 mg/m) on days 1 and 8 for two cycles, with concomitant thoracic RT (2 Gy/d, 5 d/wk, and total dose 66 Gy). Results: All patients (n = 38) who received CT-RT were assessable for the tumor response. There were no complete responses. how was the camera inventedWebDec 12, 2024 · Cisplatin Adult Medication Share This information from Lexicomp ® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Warning This drug may cause kidney problems like kidney failure. how was the cabinet createdWebApr 13, 2024 · Bonn researchers uncover contribution of protein degradation processes to cisplatin resistance in germ cell tumors: Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options. how was the byzantine empire originated