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Phenanthrol

WebThis small molecule/inhibitor is primarily used for Biochemicals applications. Synonym (s): TRPM4 inhibitor, 9-Phenanthrol, Phenanthren-9-ol, 9-Hydroxyphenanthrene Empirical Formula (Hill Notation): C14H10O CAS Number: 484-17-3 Molecular Weight: 194.23 MDL number: MFCD00082298 Pricing and availability is not currently available. Properties Web9-Phenanthrol Revision Date 24-Dec-2024 Reactive Hazard None known, based on information available Stability Stable under normal conditions. Conditions to Avoid Incompatible products. Incompatible Materials Oxidizing agent Hazardous Decomposition ProductsThermal decomposition can lead to release of irritating gases and vapors …

Pharmacological Modulation and (Patho)Physiological Roles of …

WebBiological Activity for 9-Phenanthrol. 9-Phenanthrol is a selective TRPM4 blocker (IC 50 = 20 μ M in HEK293 cells). Exhibits no effect on CFTR or TRPM5 (at 0.25 and 1 mM … Web3-Phenanthrol C14H10O CID 95724 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. National Institutes of Health. National Library of Medicine. National Center for Biotechnology Information. PubChem ... helmut sweatshirt https://carolgrassidesign.com

Frontiers The TRPM4 channel inhibitor 9-phenanthrol alleviates ...

WebThe NO/ONOO-cycle is a primarily local, biochemical vicious cycle mechanism, centered on elevated peroxynitrite and oxidative stress, but also involving 10 additional elements: NF … Webphenanthrol (plural phenanthrols) ( organic chemistry ) Any of five isomeric phenols derived from phenanthrene Retrieved from " … helmut swart

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Category:TRPM4 inhibitor, 9-Phenanthrol - CAS 484-17-3 - EMD Millipore

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Phenanthrol

Pharmacological Modulation and (Patho)Physiological Roles of …

WebPredicted data is generated using the US Environmental Protection Agency s EPISuite™. Log Octanol-Water Partition Coef (SRC): Log Kow (KOWWIN v1.67 estimate) = 3.86 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42): Boiling Pt (deg C): 363.13 (Adapted Stein & Brown method) Melting Pt (deg C): 121.39 (Mean or Weighted MP) … WebOn the contrary, 9-phenanthrol inhibited cAMP-dependent protein kinase and myosin light chain kinase of bovine heart with an IC 50 of 10 µM . Although 10 µM 9-phenanthrol did not alter the voltage-gated Ca 2+ and K + channels of primary cardiomyocytes, at 100 µM, it induced 47 and 43% reductions in these channels, respectively .

Phenanthrol

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WebProduct No. Description. SDS. Pricing. 648492. The TRPM4 inhibitor, 9-Phenanthrol, also referenced under CAS 484-17-3, controls the biological activity of TRPM4. This small … WebTransient receptor potential melastatin 4 (TRPM4) is a unique member of the TRPM protein family and, similarly to TRPM5, is Ca2+ sensitive and permeable for monovalent but not …

WebTRPM4 inhibitor, 9-Phenanthrol - CAS 484-17-3 - Calbiochem The TRPM4 inhibitor, 9-Phenanthrol, also referenced under CAS 484-17-3, controls the biological activity of TRPM4. This small molecule/inhibitor is primarily used for Biochemicals applications. - Find MSDS or SDS, a COA, data sheets and more information. Web* 更多信息,请联系营业部:021-51613951/[email protected] * 相辉医药全线产品仅供科研使用

WebFeb 3, 2024 · 9-Phenanthrol treatment alleviated brain water content and neurological deficits The chemical structure of the specific TRPM4 inhibitor is shown in Figure 1A. The brain water content of the ipsilateral hemisphere 24 h after TBI was measured to reflect the degree of cerebral edema (CE). WebFeb 6, 2024 · The higher concentration of 9-phenanthrol displayed a greater efficacy, consistent with the effects of the two concentrations tested independently (Fig. 3, A and B, and Table 1, and 30 μM data in Ref. 55). The inhibitory effects of 9-phenanthrol were concentration (30 vs. 100 μM) and membrane potential (negative vs. positive) dependent.

Web1-Phenanthrol. Molecular Formula C 14 H 10 O; Average mass 194.229 Da; Monoisotopic mass 194.073166 Da; ChemSpider ID 88945

Web1-Hydroxyphenanthrene is a phenanthrol and a human metabolite of phenanthrene that can be detected in urine of persons exposed to PAHs. It can also be used as a marker for PAH … helmut the forsaken child 11WebIn the case of calcinated agricultural soil, the following products were identified: 9,10-phenanthroquinone, catechol, phenanthrol, and diphenic acid. All of them had the concentration of 2–10 mg kg−1 ( Fig. 9.19 B). Most of the identified compounds are identical to the ones obtained in the case of calcinated sand. helmut strebl on planet earthWebNov 1, 2013 · Recently, a novel selective TRPM4 channel inhibitor, 9-phenanthrol, has been described. 9, 10, 15, 22, 23 Thus, 9-phenanthrol is an important pharmacological tool that could be used to investigate the TRPM4 channel physiological role in DSM excitability. 9, 10 Use of this novel selective pharmacological inhibitor has allowed us to show that ... helmut swoboda pdfhttp://www.delta-f.com/details/1166887 lamb christinaWebJan 16, 2014 · The phenanthrene-derivative 9-phenanthrol is a recently identified inhibitor of the transient receptor potential melastatin (TRPM) 4 channel, a Ca 2+-activated non-selective cation channel whose mechanism of action remains to be determined.Subsequent studies performed on other ion channels confirm the specificity of the drug for TRPM4. helmut thailandWeb3-Phenanthrol C14H10O CID 95724 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity … helmut : the forsaken childWebCatalog No.E0028Synonyms: 9-Hydroxyphenanthrene, Phenanthren-9-ol, 9-Phenanthrenol. For research use only. 9-Phenanthrol (9-Hydroxyphenanthrene, Phenanthren-9-o, 9 … helmut streng spedition