Sumo chains: polymeric signals
Web1 Feb 2010 · SUMO chains: Polymeric signals SUMO chains: Polymeric signals February 2010 Authors: Alfred C O Vertegaal Request full-text Abstract Ubiquitin and ubiquitin-like …
Sumo chains: polymeric signals
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WebSUMO (small ubiquitin-related modifier) shares the ability of ubiquitin to form chains via internal SUMOylation sites. Interestingly, a SUMO-binding site in Ubc9 is important for … WebPrevious studies have shown that, like ubiquitin, SUMO is able to form polymeric chains. These chains are involved in several processes, such as mitosis, meiosis and …
Web11 Oct 2010 · The role SUMO plays in meiosis remains largely unknown; however, immunolocalization studies in mammals have detected SUMO at sites of double strand breaks (DSBs) and at centromeric and heterochromatic regions, including the XY body of mouse pachytene spermatocytes [ 9, 10, 11, 12 ]. Web19 Jan 2010 · SUMO chains play roles in replication, in the turnover of SUMO targets by the proteasome and during mitosis and meiosis. Thus signalling via polymers is an exciting …
WebTarget proteins are conjugated to ubiquitin monomers or to ubiquitin polymers that form via all seven internal lysine residues of ubiquitin. The fate of these target proteins is … Webon ubiquitin polymers, we are still limited in our understanding of signaling by SUMO polymers. Highlights STUbLs recognize the composition of SUMO chains as …
Web22 Feb 2012 · Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins ( PubMed: …
WebSUMO chains: polymeric signals Alfred C.O. Vertegaal 46–49 Antiviral activity of resveratrol Michela Campagna and Carmen Rivas 50–53 SUMO and ubiquitin modifications during … mafs season 8WebInvestigations into the biological role of polymeric chains have been hampered by the absence of a protocol for the purification of proteins linked to SUMO chains. In this paper, … kitchens victoria kilsythWeb6 Feb 2024 · Author summary The Small ubiquitin-related modifier (SUMO) is a 100 amino acid protein that is attached to other proteins and thereby regulates nearly all essential … mafs secret actorsWeb1 Apr 2024 · Unfortunately, the capture of interactors such as RNF4 and RNF111 using diSUMO-2 pull-down probes proved very difficult (data shown below), mainly because the … mafs season 9 couples still togetherWebSmall ubiquitin-like modifiers (SUMOs) regulate virtually all nuclear processes. The fate of the target protein is determined by the architecture of the attached SUMO protein, which … mafs season finaleWebT1 - Decoding the SUMO signal. AU - Hay, Ronald T. PY - 2013/4. ... Like ubiquitin, SUMO can form polymeric chains, and these chains can be recognized by proteins containing … kitchens utensils waco txWeb1 Feb 2010 · SUMO chains: polymeric signals. Ubiquitin and ubiquitin-like proteins are conjugated to a wide variety of target proteins that play roles in all biological processes. … kitchens virtual tours